慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease, COPD)在全球呈高发病率、高死亡率及高致残率等特点,对公共卫生构成重大威胁。“肺与大肠相表里”理论是藏象学说的经典内容之一,揭示了肺与大肠的脏腑相关性。“肠–肺轴”作为该理论的现代阐释,为“肺与大肠相表里”理论在COPD治疗中的应用提供了科学依据。本研究通过系统整理和深入分析相关文献资料,创新性地从“肺与大肠相表里”视角探讨“肠–肺轴”在慢性阻塞性肺疾病中的作用,旨在为中医药治疗COPD提供新的理论依据和研究方向。Chronic Obstructive Pulmonary Disease (COPD) is characterized by high incidence rates, high mortality rates, and high disability rates globally, posing a significant threat to public health. The theory of “lung and the large intestine being interior-exteriorly related” is one of the classic contents of the Zang-Fu organ theory, revealing the organ-relatedness between the lung and the large intestine. The “gut-lung axis” as a modern interpretation of this theory, provides a scientific basis for the application of the “lung and large Intestine being interior-exteriorly related” theory in the treatment of COPD. This study systematically organizes and deeply analyzes relevant literature, innovatively exploring the role of the “gut-lung axis” in COPD from the perspective of “lung and large Intestine being interior-exteriorly related.” The aim is to provide new theoretical foundations and research directions for the treatment of COPD with traditional Chinese medicine.
