目的:探讨经支气管针吸活检术联合建隧活检在临床中的应用价值。方法:回顾性分析济宁医学院附属医院呼吸与危重症学科在2023年1月至2024年10月期间胸部CT/胸部增强CT示有肺门/纵隔淋巴结肿大和(或)肺周围病变的病例患者的临床资料分3组,53例行C-TBNA检查的患者为1组、31例行C-TBNA联合建隧活检检查的患者为2组、324例行EBUS-TBNA检查的患者为3组,收集上述3组患者的病理学检查结果、穿刺部位,计算敏感度、特异度、准确率。结果:行C-TBNA诊断的敏感度为79%,特异度为100%,诊断准确率为80.8%;行C-TBNA联合建隧活检诊断的敏感度为95.4%,特异度100%,准确率96.7%;行EBUS-TBNA诊断的敏感度为93.5%,特异度100%,准确率95%;3组准确率相比差异有统计学意义(χ2 = 11.532, P = 0.002, P 0.05)。结论:C-TBNA联合建隧活检诊断率高于C-TBNA,且不劣于EBUS-TBNA相比,该项技术可以用于纵隔和肺门淋巴结的诊断评估。Objective: To investigate the clinical value of transbronchial needle aspiration biopsy combined with tunnel biopsy. Methods: A retrospective analysis was performed for the clinical data of patients with hilar/mediastinal lymphadenopathy and/or peripulmonary lesions on chest CT/chest contrast- enhanced CT from January 2023 to October 2024, including 1 group of 53 patients who underwent C-TBNA, 2 groups of 31 patients who underwent C-TBNA combined with tunnel biopsy, and 3 groups of 324 patients who underwent EBUS-TBNA. The pathological examination results and puncture sites of the above three groups were collected, and the sensitivity, specificity and accuracy were calculated. Results: The sensitivity, specificity and accuracy of C-TBNA were 79%, 100%, and 80.8%. The sensitivity and specificity of C-TBNA combined with tunnel biopsy were 95.4%, the specificity was 100%, and the accuracy was 96.7%. The sensitivity and specificity of EBUS-TBNA were 93.5%, the specificity was 100%, and the accuracy was 95%. There was a stati
