目的:探讨扶正益补颗粒联合HAART治疗气血亏虚型HIV感染者的临床疗效及对免疫系统(T淋巴细胞亚群)的影响。方法:选取100例于2022年7月~11月到昆明市第三人民医院就诊的气血亏虚型HIV感染者。采用随机数字表法将HIV患者随机分为中西药组与西药组,每组各50例。西药组给予HAART治疗方案;中西药组在HAART的基础上加用扶正益补颗粒;疗程均为24周。观察两组临床疗效,比较治疗前后两组患者中医证候积分、HIV病毒载量、T淋巴细胞亚群、IFN-γ、IL-4水平及不良反应发生率。结果:治疗后,中西药组在缓解乏力、气短、神疲、懒言、面色淡白或萎黄及纳呆症状的疗效优于西药组(P P +、CD4+/CD8+均较治疗前显著升高显著(P P +显著高于西药组(P +均较治疗前降低(P γ水平均显著升高(P P Objective: To explore the clinical efficacy and impact on the immune system (T lymphocyte subpopulations) of Fuzheng Yibu Granules combined with HAART in the treatment of HIV-infected people with deficiency of qi and blood. Methods: A total of 100 HIV-infected individuals who fulfilled the diagnostic criteria for HIV infection accompanied by qi and blood deficiency were enrolled in this study and received treatment at the Third People’s Hospital of Kunming from July 2022 to November 2022. The participants were randomly allocated into two groups: the Chinese and Western medicine group and the Western medicine group, with 50 individuals in each group. The Western medicine group was given the HAART treatment;the Chinese and Western medicine group was given Fuzheng Yibu Granules on the basis of HAART. The treatment course was 24 weeks. The therapeutic effects of the two groups were observed, and the TCM syndrome scores, HIV viral load, T lymphocyte subsets, IFN-γ, IL-4 levels, and the incidence of adverse reactions before and after treatment were compared between the two groups. Results: After treatment, the Chinese and Western medicine group was super
