Based on the ordering of fuzzy numbers proposed by Goetschel and Voxman,the representations and some properties of strongly preinvex fuzzy-valued function are defined and obtained, several new concepts of strongly monotonicities fuzzy functions are introduced, the relationship among the strongly preinvex, strongly invex and monotonicities under some suitable and appropriate conditions is established and a necessary condition for strongly pseudoinvex functions is given. As an application, the conditions of local optimal solution and global optimal solution in the mathematical programming problem are discussed.