近年来,随着儿童支气管哮喘的患病率和相关死亡率在世界范围内不断增加,已然成为全球公共卫生问题,严重哮喘会带来巨大的健康、经济和社会负担。随着中、西医学者对小儿哮喘发病机制的认识不断深入,治疗手段也在不断更新优化,但小儿哮喘整体控制水平仍不容乐观。文献研究发现,临床治疗小儿支气管哮喘通过西医、中医、中西医结合疗法等可有效改善和缓解患儿病情,本文对小儿支气管哮喘的西医、中医认识和治疗进行综述,期望为该疾病的临床研究提供综合性的参考依据。In recent years, the rising prevalence and associated mortality of pediatric bronchial asthma have emerged as a significant global public health concern. Severe cases of asthma impose substantial health, economic, and social burdens. With the deepening understanding of the pathogenesis of pediatric asthma by both traditional Chinese and Western medical scholars, treatment methodologies have been continually updated and optimized. However, the overall control of pediatric asthma remains sub-optimal. Literature studies have demonstrated that the clinical management of pediatric bronchial asthma can significantly improve and alleviate symptoms through Western medicine, traditional Chinese medicine (TCM) and integrated Chinese-Western medicine therapies. This paper aims to review the current understanding and treatment approaches of both Western and TCM in pediatric bronchial asthma, with the goal of providing evidence-based insights for further research on this condition.
乳腺增生症(hyperplasia of mammary gland,HMG)中医病名为乳癖,是一种乳腺组织增生的疾病,其中医基本病机为情志失常,病机以肝内气机郁滞为主,兼有脾肾不足等,由此导致气滞、血瘀、痰凝。气、血、痰、瘀于乳络互结。西医病因病理尚未完全明确。西药目前尚无特异性疗法,中药治疗具有良好效果。文章将对乳癖的中西医病因病机进行论述,并结合临床案例及经验总结中医药治法治则及常用药物,以临床为角度基础,提出治疗乳癖的方法,并为乳癖病因病机的研究与探讨提供新思路。
乳腺增生病是一种由乳腺导管上皮细胞、乳腺腺泡及纤维结缔组织增生所致的疾病,该病多发于中年女性,但近年来具有年轻化的趋势,青年女性发病率逐年升高,同时乳腺增生及乳腺癌的总体病患数亦逐年提高,并有一定的癌变风险,被视为癌前病变。同时该病病因病机尚未完全明确,目前现代医学对于病因病机的研究主要分为两方面,一方面是激素,另一方面为信号通路,且激素与信号通路间存在相互调控影响的过程,病机较为复杂。因此,进一步明确乳腺增生的病因病机对该病进行积极防治十分重要。该文简述了乳腺增生病的症状,总结乳腺增生的病因病机及中西医对该病的认识,并论述分泌型卷曲相关蛋白1(Recombinant Secreted Frizzled Related Protein 1,SFRP1)对乳腺增生病的影响,对此进行综述探讨。